Professor Layton and I will continue to take care of the school. Don't worry about that.

If there's anything you need, you only have to ask.

[Even though she already knows he won't. He's like that. If he doesn't reply, she'll just have to find out for herself whether or not he's really made it to his house safely. At the very least he's more than likely to have housemates who are attentive.]